Journal: BMC Microbiology

Article Title: The effects of postbiotics and glycyrrhetinic acid on immune response and inflammation-related genes during H. pylori eradication therapy

doi: 10.1186/s12866-025-04191-1

Figure Lengend Snippet: a - c . Cytotoxicity results of the S.thermophilus ' (a) and L.casei ’s (b) postbiotics, and G.acid (c) on the viability of Vero cells by MTT method

Article Snippet: Fig. 3 a S.thermophilus ’ postbiotics treatment group: Mild edema of the submucosa (stars), H×E. b G.acid treatment group: Lymphoplasmocytic infiltration in the mucosa and submucosa, moderately severe infection, H×E. c L.casei ’s postbiotics treatment group: Mild lymphoplasmacytic infiltration in the submucosal region (star), H×E. d Antibiotic treatment group, H×E. e S.thermophilus ’ postbiotics plus G.acid treatment group H×E. f S.thermophilus ’ postbiotics plus Lactobacillus casei ’s postbiotics treatment group: Mild eosinophil leukocyte infiltration in the mucosal and submucosal region (arrows), H×E. g G. acid plus L.casei ’s postbiotics treatment group: Mild lymphoplasmacytic infiltration in the submucosa (star, star), H×E. h) G.acid plus antibiotic treatment group, H×E Samples from the G. acid treatment group showed moderate mucosal and submucosal lymphoplasmacytic infiltration, mild eosinophil leukocyte infiltration, and no submucosal edema (Fig. b).

Techniques:

Journal: BMC Microbiology

Article Title: The effects of postbiotics and glycyrrhetinic acid on immune response and inflammation-related genes during H. pylori eradication therapy

doi: 10.1186/s12866-025-04191-1

Figure Lengend Snippet: a . Effects of G. acid , S. thermophilus, and L.casei ’s postbiotics on TNF-alpha expression on H.pylori -infected AGS cells. b. Synergistic effects of different combinations of G.acid , S. thermophilus , and L.casei ’s postbiotics with the antibiotic group on TNF-alpha expression in H.pylori -infected AGS cells. c . Efficacy of G.acid , S.thermophilus , and L.casei ’s postbiotics on IL-6 expression in H.pylori -infected AGS cells. d . Synergistic effects of different combinations of G.acid , S.thermophilus , and L.casei ’s postbiotics on IL-6 expression in H.pylori -infected AGS cells. e . The activities of G.acid , S.thermophilus , and L.casei ’s postbiotics on IL-1 beta expression in H.pylori -infected AGS cells. f . Synergistic effects of different combinations of G.acid , S. thermophilus , and L.casei ’s postbiotics on IL-1B expression in H.pylori -infected AGS cells. g . Efficacies of G.acid , S.thermophilus , and L.casei ’s postbiotics on IL-8 synthesis in H.pylori -infected AGS cells. h . Synergistic effects of different combinations of G.acid, S.thermophilus, and L.casei ’s postbiotics on IL-8 synthesis on H.pylori infected AGS cells. i . Effects of G.acid, S.thermophilus , and L.casei ’s postbiotics on IL-10 synthesis in H.pylori -infected AGS cells. j . Synergistic effects of different combinations of G.acid, S.thermophilus , and L.casei ’s postbiotics on IL-10 expression in H.pylori -infected AGS cells. k . Comparison of the effects of G.acid , S.thermophilus, and L.casei ’s postbiotics on COX-2 synthesis with antibiotic treatment in H.pylori -infected AGS cells. l . Comparison of the synergistic effect of different combinations of G.acid , S.thermophilus , and L.casei ’s postbiotics with antibiotic treatment on the COX-2 gene expression in H.pylori -infected AGS cells. m . Effects of G.acid , S. thermophilus , and L.casei ’s postbiotics on FOX-M1 expression in H.pylori -infected AGS cells. n . Synergistic effects of different combinations of G.acid , S.thermophilus , and L.casei ’s postbiotics on FOX-M1 expression in H.pylori -infected AGS cells. o . Effects of G. acid, S.thermophilus, and L.casei ’s postbiotics on IL-33 expression in H.pylori -infected AGS cells. p . Synergistic effects of different combinations of G.acid, S.thermophilus , and L.casei ’s postbiotics on IL-33 expression in H.pylori -infected AGS cells. r . Comparison of the effect of G.acid , S.thermophilus , and L.casei ’s postbiotics on NF-kB expression level in the H.pylori -infected AGS cells with the antibiotic group. s . Comparison of the synergistic effect of different combinations of G.acid , S.thermophilus , and L.casei ’s postbiotics with the antibiotic group on the level of NF-kB expression in H.pylori -infected AGS cells. t . Comparison of gastric H. pylori bacterial load among treatment groups based on CFU counts (log₁₀ CFU/g): Demonstrating the impact of postbiotics, Glycyrrhetinic acid , and antibiotics

Article Snippet: Fig. 3 a S.thermophilus ’ postbiotics treatment group: Mild edema of the submucosa (stars), H×E. b G.acid treatment group: Lymphoplasmocytic infiltration in the mucosa and submucosa, moderately severe infection, H×E. c L.casei ’s postbiotics treatment group: Mild lymphoplasmacytic infiltration in the submucosal region (star), H×E. d Antibiotic treatment group, H×E. e S.thermophilus ’ postbiotics plus G.acid treatment group H×E. f S.thermophilus ’ postbiotics plus Lactobacillus casei ’s postbiotics treatment group: Mild eosinophil leukocyte infiltration in the mucosal and submucosal region (arrows), H×E. g G. acid plus L.casei ’s postbiotics treatment group: Mild lymphoplasmacytic infiltration in the submucosa (star, star), H×E. h) G.acid plus antibiotic treatment group, H×E Samples from the G. acid treatment group showed moderate mucosal and submucosal lymphoplasmacytic infiltration, mild eosinophil leukocyte infiltration, and no submucosal edema (Fig. b).

Techniques: Expressing, Infection, Comparison, Gene Expression

Journal: BMC Microbiology

Article Title: The effects of postbiotics and glycyrrhetinic acid on immune response and inflammation-related genes during H. pylori eradication therapy

doi: 10.1186/s12866-025-04191-1

Figure Lengend Snippet: a S.thermophilus ’ postbiotics treatment group: Mild edema of the submucosa (stars), H×E. b G.acid treatment group: Lymphoplasmocytic infiltration in the mucosa and submucosa, moderately severe infection, H×E. c L.casei ’s postbiotics treatment group: Mild lymphoplasmacytic infiltration in the submucosal region (star), H×E. d Antibiotic treatment group, H×E. e S.thermophilus ’ postbiotics plus G.acid treatment group H×E. f S.thermophilus ’ postbiotics plus Lactobacillus casei ’s postbiotics treatment group: Mild eosinophil leukocyte infiltration in the mucosal and submucosal region (arrows), H×E. g G. acid plus L.casei ’s postbiotics treatment group: Mild lymphoplasmacytic infiltration in the submucosa (star, star), H×E. h) G.acid plus antibiotic treatment group, H×E

Article Snippet: Fig. 3 a S.thermophilus ’ postbiotics treatment group: Mild edema of the submucosa (stars), H×E. b G.acid treatment group: Lymphoplasmocytic infiltration in the mucosa and submucosa, moderately severe infection, H×E. c L.casei ’s postbiotics treatment group: Mild lymphoplasmacytic infiltration in the submucosal region (star), H×E. d Antibiotic treatment group, H×E. e S.thermophilus ’ postbiotics plus G.acid treatment group H×E. f S.thermophilus ’ postbiotics plus Lactobacillus casei ’s postbiotics treatment group: Mild eosinophil leukocyte infiltration in the mucosal and submucosal region (arrows), H×E. g G. acid plus L.casei ’s postbiotics treatment group: Mild lymphoplasmacytic infiltration in the submucosa (star, star), H×E. h) G.acid plus antibiotic treatment group, H×E Samples from the G. acid treatment group showed moderate mucosal and submucosal lymphoplasmacytic infiltration, mild eosinophil leukocyte infiltration, and no submucosal edema (Fig. b).

Techniques: Infection

Journal: BMC Microbiology

Article Title: The effects of postbiotics and glycyrrhetinic acid on immune response and inflammation-related genes during H. pylori eradication therapy

doi: 10.1186/s12866-025-04191-1

Figure Lengend Snippet: a S.thermophilus’ postbiotics plus L.casei ’s postbiotics plus antibiotic treatment group: Moderate lymphoplasmacytic infiltration in the mucosal and submucosal region (star), H×E. b S.thermophilus ’ postbiotics plus G.acid plus L.casei ’s postbiotics treatment group: Moderate lymphoplasmacytic infiltration in the mucosa (star) and submucosal region (arrows), H×E. c) G.acid plus L.casei ’s postbiotics plus S.thermophilus ’ postbiotics plus Antibiotic treatment group: Moderate lymphoplasmacytic infiltration in the mucosal and submucosal region (star), H×E. d Infection control group. H.pylori colonization (arrows), 100×, H×E. e Negative control group, H×E. f) Negative control group, H×E

Article Snippet: Fig. 3 a S.thermophilus ’ postbiotics treatment group: Mild edema of the submucosa (stars), H×E. b G.acid treatment group: Lymphoplasmocytic infiltration in the mucosa and submucosa, moderately severe infection, H×E. c L.casei ’s postbiotics treatment group: Mild lymphoplasmacytic infiltration in the submucosal region (star), H×E. d Antibiotic treatment group, H×E. e S.thermophilus ’ postbiotics plus G.acid treatment group H×E. f S.thermophilus ’ postbiotics plus Lactobacillus casei ’s postbiotics treatment group: Mild eosinophil leukocyte infiltration in the mucosal and submucosal region (arrows), H×E. g G. acid plus L.casei ’s postbiotics treatment group: Mild lymphoplasmacytic infiltration in the submucosa (star, star), H×E. h) G.acid plus antibiotic treatment group, H×E Samples from the G. acid treatment group showed moderate mucosal and submucosal lymphoplasmacytic infiltration, mild eosinophil leukocyte infiltration, and no submucosal edema (Fig. b).

Techniques: Infection, Control, Negative Control